Empress Cui Qingyi of Dayong was framed by her cousin, drugged and thrown into a dilapidated temple, and lost herself to Regent Xiao Che. She married Emperor Xiao Hao for three years and was constantly deceived, thinking that Xiao Hao loved her deeply. However, she did not know that Xiao Hao had falsely recognized Xiao Che as a lifesaver for the imperial power, imprisoned Cui Qingyi's father and younger brothers, and had been causing chaos in the palace with Empress Dowager Liu Mengmeng, allowing her to falsely claim Cui Qingyi's plague medicine. After knowing everything, Xiao Che decisively decided to guide and force Cui Qingyi to awaken as quickly as possible. In addition to uncovering her true thoughts step by step, he also wanted her to become a confident and brave self again, and become the world's number one female doctor. Cui Qingyi endured humiliation and regained her medical skills, finally developing a prescription to cure the plague. She exposed Liu Mengmeng's crime of stealing the prescription in the Golden Luang Hall. However, due to the lives of her father and younger brother, Cui Qingyi was forced to be under the control of Xiao Hao, leading to constant misunderstandings between her and Xiao Che, making it difficult for her to face her true feelings. When Xiao Che was falsely accused of colluding with the enemy and betraying the country, Cui Qingyi brought evidence to expose Xiao Hao's conspiracy in the Golden Luang Hall. Xiao Che also tore open Liu Mengmeng's mask at the same time. Xiao Hao committed suicide, Liu Mengmeng was executed, and Cui Qingyi's family was rescued. In the end, Xiao Che ascended to the throne as the new emperor, quelled the rebellion of Medicine King Gu, and worked together with Cui Qingyi to quell epidemics and wars. Cui Qingyi achieved the dual identity of the world's first empress and divine physician from the cage.
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